Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014936
Fusion event
HBV-ADAM32 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
2148
Orient
+
Integrated sequence
ACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGA| |GACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTA
Host Sequence
Chromosome
chr8
Cytoband
p11.22
Reference genome
Start
End
39087853/39230334 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-124-1/Upstream/9272986; hsa-mir-10400/Downstream/2040714;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/122430, chr8-CpG: 30/Downstream/292372
Upstream sequence
ttggaggccttagctcacaaggggaaaaatgtttctaacaggagatacaaaaacaatctcaatgaattgaaagtttagacctatctctgattatttgggg
Downstream sequence
TACTAATGGGAGAGAGCGTTTAAGGGAGAAATTAATGAGAGGGGGTTATTGGTAACTTTAGATGCCACACGTAGACTAATAAAATTGAGTTGGTTGGCGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.