Basic Information
VIS ID
TVIS10014940
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Start
59
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCC| |TGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATG
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
220807737/219943016 (Hg38)
End
220807737/219943016 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/36451; hsa-mir-1244-1/Downstream/5067445;
Nearest TSS
ENST00000437798/Upstream/38127; ENST00000438633/Downstream/162640;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/314951, chr2-CpG: 260/Downstream/1627994
Nearby gene
LOC105373890(-2244) ; LOC105373891(+4804) ;
Upstream sequence
gctctgatttttattatgtccttcttactgctaactttgggctgaagtttgttctttttctggttccttgaggtttgtagttaggttgtttatctgagat
Downstream sequence
ctctttgttcttaatgtaggcattcatacctataaatttccatcttagaatagcttttgctgcattttgtaaatctcagtatgttttgtttacattttgt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate