Basic Information
VIS ID
TVIS10014942
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
455
Orient
-
Integrated sequence
CAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTA| |TCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATG
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
End
157678671/156757519 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/4221003; hsa-mir-1305/Downstream/2371283;
Nearby gene
Upstream sequence
ttttagatatgctgaagccctttaagtggagctgcctggagttctgtggcaaaatgggaaaaatgcctctcccttatgttattccctctcagagttgcac
Downstream sequence
TCTGTAACTTTAAAAAGAGTTATCTGAGATATCTGTCATGGTACCTGAGATAGGGTTGACAGGAAAGTCATTCACTGGAAAACCAAACACATTCTCAAAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate