Fusion event
HBV-chr4 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Integrated sequence
CAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTA| |TCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATG
End
157678671/156757519 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/4221003; hsa-mir-1305/Downstream/2371283;
Upstream sequence
ttttagatatgctgaagccctttaagtggagctgcctggagttctgtggcaaaatgggaaaaatgcctctcccttatgttattccctctcagagttgcac
Downstream sequence
TCTGTAACTTTAAAAAGAGTTATCTGAGATATCTGTCATGGTACCTGAGATAGGGTTGACAGGAAAGTCATTCACTGGAAAACCAAACACATTCTCAAAG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.