VISDB Viral Integration Site DataBase

VIS ID

TVIS10014943

Fusion event

HBV-XKR6 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

1929

Orient

+

Integrated sequence

CCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTT| |GGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAG

Chromosome

chr8

Cytoband

p23.1

Reference genome

Start

End

10875912/11018402 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-218-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-4795-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-7850-5p ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-122-5p ; hsa-mir-5582-3p ; hsa-mir-504-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-4455 ; hsa-mir-3924 ; hsa-mir-6074

Nearest miRNA

hsa-mir-124-1/Upstream/192959; hsa-mir-10400/Downstream/16804;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/1625, chr8-CpG: 76/Downstream/40750

Upstream sequence

gccaataataaattttaagcaagagaccaacataaactgattttctagtaagaaagcactcttggaaggtagtgagaaggatatattgggagtgggaggc

Downstream sequence

AAACTCAGGAAGGGAGCGATGGCAAGAGAGGGAGGCCAGATGACAGATACCTCCACCACCGGGCCTCCAGGCTAGCACTTCCCTCCATAATATGGGGGTC