Basic Information
VIS ID
TVIS10014947
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1762
Orient
-
Integrated sequence
GACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA| |AAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTAC
Host Sequence
Chromosome
chr13
Cytoband
q12.12
Reference genome
GRCh37/hg19
Start
24964482/24390344 (Hg38)
End
24964482/24390344 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/227840; hsa-mir-1267/Downstream/15273690;
Nearest TSS
ENST00000623511/Upstream/58894; ENST00000218548/Downstream/64790;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/49382, chr13-CpG: 62/Downstream/122040
Upstream sequence
CTCCGAGTGGGACAAGCGAGCGTTCTCGTTTCTAGGATGATCAAGTTTTGCCAGAGCTTGAGCAAAGCTACTCAGTCATGAGATTGGAAGGTGGGAGCCC
Downstream sequence
CACGTGGCTGGAACTTCATTCCTGCAGAGAAGATCCCTCCAGAGAGGCCCCAGGCCCAGCTACGGAAATAAATGCAGCCACACCCCATTCCCCTTCAGAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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