Basic Information
VIS ID
TVIS10014950
Fusion event
HBV-chr9 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1657
Orient
+
Integrated sequence
TGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACAT| |AAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTA
Host Sequence
Chromosome
chr9
Cytoband
q13
Reference genome
GRCh37/hg19
Start
66971323/63066351 (Hg38)
End
66971323/63066351 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA9F
Nearest miRNA
hsa-mir-101-2/Upstream/21832516; hsa-let-7a-1/Downstream/7743624;
Nearest TSS
ENST00000422679/Upstream/168245; ENST00000431077/Downstream/662526;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/150306, chr9-CpG: 299/Downstream/382519
Nearby gene
BMS1P9(-7134) ;
Upstream sequence
TTCATCATTTAGAAAATATTTCTAACAAATATTTAGGTTGAATACCTAGTCATGCATTATAATAAATAACTATTTAATCTTTTCTTTTTTTGTTTTCACG
Downstream sequence
ctgtcagttgagtacacacatcacaaacaagtttctgagaatgcttctgtctagtttttatgggaagatatttcctttttcaccataggccacaaagcgc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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