VISDB Viral Integration Site DataBase

VIS ID

TVIS10014954

Fusion event

HBV-GRM1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp3 X protein

Start

1567

Orient

-

Integrated sequence

GGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCA| |TCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTC

Chromosome

chr6

Cytoband

q24.3

Reference genome

Start

End

146729115/146407979 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-1281 ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-3187-5p ; hsa-mir-5189-5p ; hsa-mir-1285-3p ; hsa-mir-5193 ; hsa-mir-660-3p ; hsa-mir-5196-3p

Nearest miRNA

hsa-mir-10398/Upstream/5724096; hsa-mir-1202/Downstream/4694696;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/378335, chr6-CpG: 44/Downstream/26360

Nearest cancer related gene

GRM1(OG, No orient, 0)

Upstream sequence

taaattgttttcgcaggatcacagataagactttggacttttgagttgttgctggaataagttaagaccttggggctatgaagatagaataaatgtattt

Downstream sequence

gctataactaaaatatcatagactgggtgacttaagagcagaaatatattgctcacagttctggaggctgagaagtcctagattagggtgctagcaggtg