Basic Information
VIS ID
TVIS10014958
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
2730
Orient
+
Integrated sequence
AATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTA| |CTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCT
Host Sequence
Chromosome
chr8
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
91482800/90470572 (Hg38)
End
91482800/90470572 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12123/Upstream/10229099; hsa-mir-10400/Downstream/734913;
Nearest TSS
ENST00000518652/Upstream/249034; ENST00000519233/Downstream/135493;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/468534, chr8-CpG: 159/Downstream/174589
Upstream sequence
tgctggtctcccctgctgggccacaggctctgttaagggcagggactgcgtcagacttcaaaacttggaggaaaataaatgctaatcagtgttttctaag
Downstream sequence
TGATGAAAGTCACATGGGATTCTCCAAATCATTTTTCTTCCTCCTTTAGCTTAGAAGCCTAGAAGGTTGATGATTCTTCTTAGAATGAAACTATCCTCCG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate