Basic Information
VIS ID
TVIS10014961
Fusion event
HBV-chr10 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein;HBVgp4 precore/core protein
Start
1832
Orient
+
Integrated sequence
TGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCT| |CTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGA
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42391029/41849178 (Hg38)
End
42391029/41849178 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6207926; hsa-mir-107/Downstream/1148385;
Nearest TSS
ENST00000439456/Upstream/3395997; ENST00000442306/Downstream/336161;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2906072, chr10-CpG: 184/Downstream/261855
Upstream sequence
aatggaattatcgaatgcaatcgagtagaatcatcgaatggactcgaatggtatcatcgaatggaacggaatggaatagtcaatgaactcgaatggaatc
Downstream sequence
atcattgaatggaatcgaatggaatcatcgagtggaatcgaatggaatcacgattaaatggaatcgaatgtaatcatcaaatggaatcaaaaataacaat
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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