VISDB Viral Integration Site DataBase

VIS ID

TVIS10014963

Fusion event

HBV-TJP1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein;HBVgp4 precore/core protein

Start

1838

Orient

+

Integrated sequence

GAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCT| |AATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACT

Chromosome

chr15

Cytoband

q13.1

Reference genome

Start

End

30215085/29922882 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-212-3p ; hsa-mir-155-5p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-17-5p ; hsa-let-7b-5p ; hsa-mir-105-5p ; hsa-mir-4799-5p ; hsa-mir-194-5p ; hsa-mir-383-3p ; hsa-mir-548c-3p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-379-3p ; hsa-mir-411-3p ; hsa-mir-802 ; hsa-mir-4801 ; hsa-mir-5700 ; hsa-mir-4731-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-212-5p ; hsa-mir-34c-5p

Nearest miRNA

hsa-mir-1268a/Upstream/1432037; hsa-mir-10393/Downstream/1142150;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/99870, chr15-CpG: 97/Downstream/45410

Upstream sequence

CAGTGTAATAATGATAATTAACAGTAACAAGATATTGTTAAAATTTTAATTAAACTTAAAGCAGCAGCAGGAAATACTGAAAAATAAAATACTTGGCTAC

Downstream sequence

ATAAAAATGTACACTTCTACTTACTTCTAACCTTATAaattctaaaagaaaaaacacaaatggtaaaacacatatgaaaaaactgtttaatctgaacagt