VISDB Viral Integration Site DataBase

VIS ID

TVIS10014965

Fusion event

HBV-MAP2K3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp3 X protein

Start

1619

Orient

+

Integrated sequence

CACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCA| |CCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTG

Chromosome

chr17

Cytoband

p11.2

Reference genome

Start

End

21201604/21298292 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-214-3p ; hsa-mir-20a-5p ; hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-mir-21-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-218-5p ; hsa-mir-1227-5p ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-1296-3p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-28-5p ; hsa-mir-2861 ; hsa-mir-3139 ; hsa-mir-3151-5p ; hsa-mir-3619-5p ; hsa-mir-424-5p ; hsa-mir-4270 ; hsa-mir-4441 ; hsa-mir-4456 ; hsa-mir-4481 ; hsa-mir-4512 ; hsa-mir-4743-5p ; hsa-mir-4745-5p ; hsa-mir-497-5p ; hsa-mir-541-3p ; hsa-mir-5571-3p ; hsa-mir-6081 ; hsa-mir-6510-5p ; hsa-mir-654-5p ; hsa-mir-6731-5p ; hsa-mir-6742-5p ; hsa-mir-6754-5p ; hsa-mir-6760-5p ; hsa-mir-6762-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6781-5p ; hsa-mir-6838-5p ; hsa-mir-6845-5p ; hsa-mir-6877-5p ; hsa-mir-708-5p ; hsa-mir-761 ; hsa-mir-8085 ; hsa-mir-92a-2-5p

Nearest miRNA

hsa-mir-1180/Upstream/1953718; hsa-mir-10226/Downstream/5995618;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/13161, chr17-CpG: 47/Downstream/18387

Upstream sequence

cctccaggcctgggtctgtcctgctctgctcccctgcaGGGCTGGTGGGCCTCCTTCCCCCTTTGAAGGCCTAACGGCCTGGCTTGGAGAGAGGGGGCTC

Downstream sequence

CCGGCATGGGTGATGGCAGAGGCTGGCACCCTTGTGGGCCAGGGCCTGATGGCTCATGGGAGTGCAGGGGACATTGATGTCAAGGGATAGGCCAGACGCC