Basic Information
VIS ID
TVIS10014970
Fusion event
HBV-chr11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S1/pre-S2/S
Start
2983
Orient
-
Integrated sequence
GATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAA| |CAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCA
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
62426036/62658564 (Hg38)
End
62426036/62658564 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/91493; hsa-let-7a-2/Downstream/131251;
Nearest TSS
ENST00000527297/Upstream/5262; ENST00000594728/Downstream/6614;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/5112, chr11-CpG: 94/Downstream/6283
Nearby gene
C11orf98
Upstream sequence
CAACTTCTAACAGTTCCTAGAACACAGTAAGTTCCTTTTCCCTGTTAGGCACAGAGAGAACAAAACTATGAAGGATTGAGCATGCCAAGCCGTTGAAAAT
Downstream sequence
GTctttctttctctttcctatctcctcctctcctttccttACTGCATCTGAACACAGTTCAATTTCttttcgttttttttttttgttttttttttgagat
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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