Basic Information
VIS ID
TVIS10014971
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
734
Orient
+
Integrated sequence
AATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTC| |AGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATT
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
57280755/56886971 (Hg38)
End
57280755/56886971 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/2549657; hsa-let-7i/Downstream/307533;
Nearest TSS
ENST00000382841/Upstream/101042; ENST00000622922/Downstream/47434;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/134422, chr12-CpG: 79/Downstream/119113
Upstream sequence
aatgactgcccttctgggttttggacttgcatggggcctgtagtccctttgttttggctgatttttcccttttggaatgagtgtacttacccaatgcctg
Downstream sequence
tagccccattatatcttggaagtgactaacttgttttttattttacagggtcataggtggaagggacttgcctggtctcatatgagacttttggttgtga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate