VISDB Viral Integration Site DataBase

VIS ID

TVIS10014975

Fusion event

HBV-RBM25 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

1955

Orient

+

Integrated sequence

GTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTT| |TTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCAC

Chromosome

chr14

Cytoband

q24.2

Reference genome

Start

End

73560650/73093942 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-513b-5p ; hsa-mir-6072 ; hsa-mir-6891-3p ; hsa-mir-653-5p ; hsa-mir-5190 ; hsa-mir-4719 ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-551b-5p

Nearest miRNA

hsa-mir-208a/Upstream/577044; hsa-mir-1185-1/Downstream/664805;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/34898, chr14-CpG: 72/Downstream/42248

Upstream sequence

CAGAAAATCGTGTATAGTTGATATTCCAGAGATAGAGCTTTAGATGAAACTTGCCAGTCTGTGGAGTGGTCTTTCTAACCTGATCATCTACCATGATCAG

Downstream sequence

Gttttgttttttttttttttttttcttgagacagagtctcactctgtcgcccaggctggagtgcagtggcgcgatctcagctcactgcaagctccgcctc