VISDB Viral Integration Site DataBase

VIS ID

TVIS10014977

Fusion event

HBV-NCAN integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S

Start

66

Orient

-

Integrated sequence

AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGT| |GGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACA

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

19341571/19230762 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-342-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-377-3p ; hsa-mir-711 ; hsa-mir-1286 ; hsa-mir-186-3p ; hsa-mir-4530 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6165 ; hsa-mir-24-3p ; hsa-mir-1911-3p ; hsa-mir-4305 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4733-3p ; hsa-mir-4742-5p ; hsa-mir-4777-5p ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-6502-3p

Nearest miRNA

hsa-mir-10395/Upstream/844128; hsa-let-7e/Downstream/204301;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/5420, chr19-CpG: 98/Downstream/27147

Upstream sequence

ATGCAGGTTTCATCATCCAGCCTGTCACTTCTGGGCTGTGTTGGGGTGGGATCTtttttttttttttccttttttttttttttccagacagggtcttggt

Downstream sequence

cagttgttcaggctggagtgcagtggtgcaatcatagctcactgcaccgaggctcaagtgatcctcccacatcagcttctccagtagcttggactacagg