VISDB Viral Integration Site DataBase

VIS ID

TVIS10014978

Fusion event

HBV-NCAN integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S1/pre-S2/S

Start

2986

Orient

-

Integrated sequence

TCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAA| |GGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCA

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

19341767/19230958 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-342-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-377-3p ; hsa-mir-711 ; hsa-mir-1286 ; hsa-mir-186-3p ; hsa-mir-4530 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6165 ; hsa-mir-24-3p ; hsa-mir-1911-3p ; hsa-mir-4305 ; hsa-mir-4645-5p ; hsa-mir-4673 ; hsa-mir-4733-3p ; hsa-mir-4742-5p ; hsa-mir-4777-5p ; hsa-mir-518d-5p ; hsa-mir-518e-5p ; hsa-mir-518f-5p ; hsa-mir-519a-5p ; hsa-mir-519b-5p ; hsa-mir-519c-5p ; hsa-mir-520c-5p ; hsa-mir-522-5p ; hsa-mir-523-5p ; hsa-mir-526a ; hsa-mir-6502-3p

Nearest miRNA

hsa-mir-10395/Upstream/844324; hsa-let-7e/Downstream/204105;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/5616, chr19-CpG: 98/Downstream/26951

Upstream sequence

caggcatgcaaccaccacacccggctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagagatggggtctccctatgttatccaggc

Downstream sequence

tggtctcaaactcctgggctcaagtgatcctcttgccttggcctcccaaagtgttgggattacagacatgagccgtagcgccgggcAGTTCTTTTTTTCT