VISDB Viral Integration Site DataBase

VIS ID

TVIS10014979

Fusion event

HBV-TM6SF2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2654

Orient

+

Integrated sequence

CATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTT| |ATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACA

Chromosome

chr19

Cytoband

p13.11

Reference genome

Start

End

19379764/19268955 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-4769-5p ; hsa-mir-1273h-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-542-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-2277-3p ; hsa-mir-2467-5p ; hsa-mir-134-3p ; hsa-mir-6081

Nearest miRNA

hsa-mir-10395/Upstream/882321; hsa-let-7e/Downstream/166108;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/6051, chr19-CpG: 63/Downstream/3939

Upstream sequence

tggagtgcagtgatgcaatcttggctcactgcaacctctgcctcccaggttcaagcaattctcttgtctcagcctcctgagtagctgggattatacctgg

Downstream sequence

ctaatttttgtacttttagtataggcagggtttcaccatgctgcccaggctgatcttgatctccacggctcaagtgatTGATgaggcaggtggattgctt