VISDB Viral Integration Site DataBase

VIS ID

TVIS10014990

Fusion event

HBV-ARID1B integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1798

Orient

-

Integrated sequence

TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTG| |GTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTG

Chromosome

chr6

Cytoband

q25.3

Reference genome

Start

End

157209000/156887866 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-92b-3p ; hsa-mir-324-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-578 ; hsa-mir-643 ; hsa-mir-138-2-3p ; hsa-mir-5692a ; hsa-mir-552-5p ; hsa-mir-302c-5p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-mir-3143 ; hsa-let-7a-3p ; hsa-mir-656-3p ; hsa-mir-144-3p ; hsa-mir-602 ; hsa-mir-543

Nearest miRNA

hsa-mir-10398/Upstream/108135; hsa-mir-1913/Downstream/641266;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/167662, chr6-CpG: 134/Downstream/133060

Upstream sequence

TCTGATTCCCGAGACTCTCTTGATTCATTTAATGGTTTATGCTAGGTAAATATTTCTTGAAATTCTCCTTCTCTTTGAGTGTGGTCAGCAGCAGGCAAAC

Downstream sequence

GTGGCCTGCAGTGAATGGTCTCGCTCCTCCTGTTCCCCTACAAGGCTCCCCTTCCAAATTGGAAGATACCAGTTGCTTGTCTTTTTGTTGACTCTTTTAA