ACBD6 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10014992
Fusion event
HBV-ACBD6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
196
Orient
+
Integrated sequence
CTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCG| |TGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGT
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
180361678/180392543 (Hg38)
End
180361678/180392543 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACBD6
miRNAs that regulate target gene
hsa-mir-193b-3p
Nearest miRNA
hsa-mir-101-1/Upstream/588518; hsa-mir-1182/Downstream/45771;
Nearest TSS
ENST00000473358/Upstream/116319; ENST00000442621/Downstream/20845;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/156703, chr1-CpG: 92/Downstream/109647
Upstream sequence
GAAAATGAAATATATACAAATTTTACAGTGAATAggttaagagcttgggctttggagtcagaatattcaaatctaggctttggccttcactagctctata
Downstream sequence
acttctttaggctcctgcttcttcaccagtaaaatgtagagcataatatatgcacattatggcattgatgcaatgactaaaagagacaatgcacataaaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate