Basic Information
VIS ID
TVIS10014993
Fusion event
HBV-chr2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1627
Orient
-
Integrated sequence
GCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAAC| |GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA
Host Sequence
Chromosome
chr2
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
226810125/225945409 (Hg38)
End
226810125/225945409 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/934869; hsa-mir-1244-1/Downstream/713301;
Nearest TSS
ENST00000437798/Upstream/246895; ENST00000607970/Downstream/239962;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/362394, chr2-CpG: 74/Downstream/845778
Upstream sequence
gtggctaacggctataatcccagtactgtgggagatcgaggtgggcggatcacttgaggtcaggagttcaagaccagcctggccaacatagtgaaacctc
Downstream sequence
ctctctactaaaaatacaaaaattagccagcctttgtggtgggcgcatgtaatcccagctattcgggaggctgaagcagaagaatctcttgaacctagga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate