Basic Information
VIS ID
TVIS10015005
Fusion event
HBV-LOC285626 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1852
Orient
+
Integrated sequence
GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT| |CATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTC
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
158787996/159360988 (Hg38)
End
158787996/159360988 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC285626
Nearest miRNA
hsa-mir-10397/Upstream/4531448; hsa-mir-103a-1/Downstream/1113414;
Nearest TSS
ENST00000502646/Upstream/14888; ENST00000636261/Downstream/60226;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/29157, chr5-CpG: 57/Downstream/412242
Upstream sequence
GGGCAGCTCTACACGGCCGCGAACAGAAGTACAGGGTTTCAGCTTAAAAACAGACCTGCTGCCCACCAAGGGCCCTGTGATCCTGGCCAAACACCGTTTG
Downstream sequence
atgtaatcaaaaactatctgtacccccaaaactattgaaataaaaaaaaaatgaatgtgacacagtcctatatgtatttggcaactagccccaagttggg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate