Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015010
Fusion event
HBV-CELA3A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase
Start
1219
Orient
+
Integrated sequence
TTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGT| |CATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCA
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
Start
End
22328747/22002254 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12136/Upstream/1013822; hsa-mir-101-1/Downstream/263985;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/64470, chr1-CpG: 22/Downstream/23170
Upstream sequence
TTGACTGACAATAATGGtaacagataacattgattgagtgcttactatgccaggcagaatgtttagggattttcttatactttctcatgtaattctcaca
Downstream sequence
acagcctcaggagatcagtactatcattatcccccattttactgaccctcaaggaagtaaagtagcttatcatagaacaaaaggcagagctgcacttaat
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.