Basic Information
VIS ID
TVIS10015012
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1106
Orient
+
Integrated sequence
TCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCA| |ACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTG
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
79544313/78834596 (Hg38)
End
79544313/78834596 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/295287; hsa-mir-1202/Downstream/11478146;
Nearest TSS
ENST00000381078/Upstream/21293; ENST00000607739/Downstream/32876;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1183969, chr6-CpG: 46/Downstream/32845
Upstream sequence
tgtcctcgggacatagcgactggtgatgaccacacaatcaacacaataaactctagcattcacattgtagtccagctcattcaagcaaagctatctccaa
Downstream sequence
AAAATAAACTATTCATTATAATTAAAAATTTTACTCATATGGTTTAAATGATCAGAAAGCAATAAACATAAAATTTCATATTTCATATCTAAAATAATAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate