VISDB Viral Integration Site DataBase

VIS ID

TVIS10015014

Fusion event

HBV-NCALD integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1734

Orient

-

Integrated sequence

AAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTG| |GGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCT

Chromosome

chr8

Cytoband

q22.3

Reference genome

Start

End

103093692/102081464 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-2053 ; hsa-mir-6780a-3p ; hsa-mir-4775 ; hsa-mir-569 ; hsa-mir-4635 ; hsa-mir-32-3p ; hsa-mir-203a-3p

Nearest miRNA

hsa-mir-12123/Upstream/1378440; hsa-mir-10400/Downstream/43968;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/587262, chr8-CpG: 81/Downstream/42222

Upstream sequence

acatatgaaatttggggaaaaatttttcagcccatgacaCCTACTTGACGTTCACTTTGAGGCCTGAAAAATCCAGATTTATTGTAAAGTTAAATCATTT

Downstream sequence

CAAACGGGCCCTGGGCTTCAAAACAGTTTAGCTCATTTACGCCTATTTCTGATTTAAGTCAAGGAGAATTCAAATAATGGTaaaaaaaaaaaaaaaaaaa