VISDB Viral Integration Site DataBase

VIS ID

TVIS10015015

Fusion event

HBV-ATRNL1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1807

Orient

-

Integrated sequence

CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA

Chromosome

chr10

Cytoband

q25.3

Reference genome

Start

End

117316330/115556820 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA10D ; FRA10A ; FRA10B

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-379-3p ; hsa-mir-3613-3p ; hsa-mir-3163 ; hsa-mir-577 ; hsa-mir-6771-3p ; hsa-mir-4282 ; hsa-mir-548as-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-107/Upstream/1382641; hsa-mir-202/Downstream/1270668;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/462485, chr10-CpG: 18/Downstream/568482

Upstream sequence

ATATGTAATATAAAGAATGATCAGCATTATACATTAATATTACTAACAACAACTCCTGTATATCTTGGACTCCTCCTCCATTTCTACTGTAATGcaatgg

Downstream sequence

ttctcaatctagtaggcccttgagaatcacctgtggatctttaaaatgtgtgtgtgcgtgtgtgtatctgtgtgtatgtgtgtatttgcatgccattcta