VISDB Viral Integration Site DataBase

VIS ID

TVIS10015016

Fusion event

HBV-GAS7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2816

Orient

+

Integrated sequence

CTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTG| |GGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCT

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

10013676/10110359 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-1255b-5p ; hsa-mir-6744-5p ; hsa-mir-1255a ; hsa-mir-1287-5p ; hsa-mir-4487 ; hsa-mir-450b-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3124-3p ; hsa-mir-6837-3p

Nearest miRNA

hsa-mir-1253/Upstream/1923355; hsa-mir-10226/Downstream/1971540;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/205337, chr17-CpG: 142/Downstream/87358

Upstream sequence

ctggaggttattatgttaagttaaataagccaggcatagaaagacaaagatcagtgttctcactgatatgtaggagctaaaaaagttgctctcgtggaga

Downstream sequence

tgagagtagatagttaactagaggctaggaagggtgtgtgggaaagaggggggatgaagagagtttggttaaggggtacaaacatacagttagacagaag