GAS7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015017
Fusion event
HBV-GAS7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Start
1
Orient
+
Integrated sequence
A| |ATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGAC
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
10013673/10110356 (Hg38)
End
10013673/10110356 (Hg38)
Orient
-
Location type
Intronic
Target gene
GAS7
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-1255b-5p ; hsa-mir-6744-5p ; hsa-mir-1255a ; hsa-mir-1287-5p ; hsa-mir-4487 ; hsa-mir-450b-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-3124-3p ; hsa-mir-6837-3p
Nearest miRNA
hsa-mir-1253/Upstream/1923352; hsa-mir-10226/Downstream/1971543;
Nearest TSS
ENST00000595228/Upstream/48977; ENST00000609088/Downstream/4197;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/205334, chr17-CpG: 142/Downstream/87361
Upstream sequence
gaactggaggttattatgttaagttaaataagccaggcatagaaagacaaagatcagtgttctcactgatatgtaggagctaaaaaagttgctctcgtgg
Downstream sequence
agatgagagtagatagttaactagaggctaggaagggtgtgtgggaaagaggggggatgaagagagtttggttaaggggtacaaacatacagttagacag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate