Basic Information
VIS ID
TVIS10015019
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp3 X protein
Start
1467
Orient
-
Integrated sequence
TCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTC| |GGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCA
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21743132/22216526 (Hg38)
End
21743132/22216526 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/2871952; hsa-mir-10226/Downstream/5077384;
Nearest TSS
ENST00000595228/Upstream/524003; ENST00000578881/Downstream/49803;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/372063, chr17-CpG: 22/Downstream/743
Nearby gene
FTLP13(+4694) ;
Upstream sequence
attacaggagtgagccacggcgctgggcttttttttttttttctttttagacggagtcttgctctgttgcccaggctggagtgccttggtgctatctcag
Downstream sequence
ctcactgcaaactccgcctcccaggttcatgccattctccggcctcagcctcccaagtagctgggactacaggcgcccaccaccacgcccggctaatttt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate