Basic Information
VIS ID
TVIS10015020
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1059
Orient
+
Integrated sequence
CCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGC| |CTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCG
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21987709/22488380 (Hg38)
End
21987709/22488380 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/3143806; hsa-mir-10226/Downstream/4805530;
Nearest TSS
ENST00000595228/Upstream/68358; ENST00000540040/Downstream/34731;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/33419, chr17-CpG: 30/Downstream/29063
Upstream sequence
CCTCACCTTTTAAAATTCCCAACTTGCATGTCCTCCTGCCACTGCATTGGTGCTGACTTCTAAAGGAGCAGCGGACGTGAAAAAGTTGACTTTCTTCTAG
Downstream sequence
GTTAACTTCATGAAGATTATTAAAGTGATGAAAATATTTATCCTATTCTCTATAAAGCTCCAGCGAATATGGTTTTCTGCACATGCTTATCAAAGAATCT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate