Basic Information
VIS ID
TVIS10015022
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1857
Orient
+
Integrated sequence
GGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGT| |CCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTT
Host Sequence
Chromosome
chr17
Cytoband
q23.2
Reference genome
End
60408830/62331469 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/2288364; hsa-mir-1250/Downstream/612746;
Upstream sequence
TGAATGTGATGATGGATGAAGTTAAAAATGTTACAGGTGAGTGAGATGTTACAGTAAATACTACATTGTGTGATCTTAAAGTTTTATATGGAACTATATT
Downstream sequence
TTTAACACAATAATGTTTCTTCCactcatttatttaacaattatttatagagtatttaccacatgccaggcattgttccaggcatataggctacatcagt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate