VISDB Viral Integration Site DataBase

VIS ID

TVIS10015023

Fusion event

HBV-FN1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2258

Orient

+

Integrated sequence

TCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTT| |GGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGA

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216298193/215433470 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1675311; hsa-mir-1244-1/Downstream/2467043;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/121061, chr2-CpG: 43/Downstream/2074

Upstream sequence

CAGTCCCAGATCATGGAGTCTTTAGGACGCTCATAAGTGTCACCCACTCGGTAAGTGTTCCCAGTGTACTTGTCAAAGCAAGTCTCTTCAGCTGAGGGGA

Downstream sequence

AAAGGAAAGTCCATGTGAGCCTCACTTAGGTACAAGCTTTTCTAGTTCACTAATCCCCTCTAAAGGAAAACCCACTTCTCTATTCCACAAGTAACATGGT