VISDB Viral Integration Site DataBase

VIS ID

TVIS10015024

Fusion event

HBV-CYB5R4 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1689

Orient

+

Integrated sequence

GCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAAC| |GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG

Chromosome

chr6

Cytoband

q14.2

Reference genome

Start

End

84588522/83878803 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-373-3p ; hsa-mir-148b-3p ; hsa-mir-26b-5p ; hsa-mir-3201 ; hsa-mir-555 ; hsa-mir-3185 ; hsa-mir-32-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-4303 ; hsa-mir-6740-3p ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4778-3p ; hsa-mir-3182 ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-1250-3p ; hsa-mir-4438 ; hsa-mir-5089-5p ; hsa-mir-5095 ; hsa-mir-6504-3p ; hsa-mir-6768-5p ; hsa-mir-6807-5p ; hsa-mir-7151-3p

Nearest miRNA

hsa-mir-10398/Upstream/5339494; hsa-mir-1202/Downstream/6433939;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/18903, chr6-CpG: 61/Downstream/154835

Upstream sequence

AGGGTTGCTTGATAAAATACAGGATGCTCAttggaacatacgtttactaaaaattattatttttaatctgaaatttaaatttaactggacattttgtatt

Downstream sequence

ttgctattgttaccatcagtgtaccacagacttcaaattcctccagtggtgggccactgctaccttggttttaattcagggcctgcaatgctagagggtt