Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015027
Fusion event
HBV-NBAS integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1912
Orient
+
Integrated sequence
ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG| |ACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCT
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
Start
End
15512470/15372346 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-3125/Upstream/2634902; hsa-mir-10b/Downstream/3976083;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/736661, chr2-CpG: 27/Downstream/188669
Upstream sequence
AAGAGAAAAGCATATACATATACACACACAAAAATATTTCACAGAAGACTCACACATAGGGAGTCATTTTTACATGCGACTTCTGTTCCTGTTTTCAATT
Downstream sequence
GGCTCATTGATTATAATTTAGTTAGAACTGCTAGCCTTTACTTGATGAGAAACAGCAACTCCTGGAGTGTAGGCAAAGAAGGCTTCAAAACAAAGCAAAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.