Basic Information
VIS ID
TVIS10015031
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1035
Orient
+
Integrated sequence
ATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACAC| |AATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATA
Host Sequence
Chromosome
chr1
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
121360123/121618325 (Hg38)
End
121360123/121618325 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/4523597; hsa-mir-1182/Downstream/24232262;
Nearest TSS
ENST00000473358/Upstream/37801; ENST00000443018/Downstream/21882187;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/98598, chr1-CpG: 312/Downstream/3467184
Upstream sequence
aaactgctccacccaaaggaatgttcagctctgtgagttaaactcaatcatcacaaagtattttctgagaatgcttctgtccagtttttacatgaagctg
Downstream sequence
tttcctttactaccgtaggcctcaaagcgttccaaatctccacttgcagatactacgaaaagagcgattcagcctgaactcacaagggaaggttcaactc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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