VISDB Viral Integration Site DataBase

VIS ID

TVIS10015033

Fusion event

HBV-DMD integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2019

Orient

+

Integrated sequence

TAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGG| |GAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGG

Chromosome

chrX

Reference genome

Start

End

31469842/31469842 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-31-5p ; hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-4446-5p ; hsa-mir-186-3p ; hsa-mir-561-3p ; hsa-mir-6499-3p ; hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-2052 ; hsa-mir-8068 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-3973 ; hsa-mir-511-3p ; hsa-mir-9-3p

Nearest miRNA

hsa-mir-23c/Upstream/1895484; hsa-let-7f-2/Downstream/1113814;

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/202940, chrX-CpG: 36/Downstream/2256471

Nearest cancer related gene

DMD(TSG, No orient, 0)

Upstream sequence

gccgaggcgggcggatcacaaggtcaggagatcaagaccaccctggctaacacggtgaaaccccTCGATGATAGTTccattcgattctatgcgatgattc

Downstream sequence

CAAAGGGGATACTTTGCAGACTGAGCGAATACAACCCTCTGCCTTTAGTATCACTTATGCTTCTGGTAGAGACATTCTCGACAATAAATTATGCCATTGA