VISDB Viral Integration Site DataBase

VIS ID

TVIS10015035

Fusion event

HBV-DGKG integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein;HBVgp4 precore/core protein

Start

1836

Orient

+

Integrated sequence

AGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGC| |CTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTA

Chromosome

chr3

Cytoband

q27.3

Reference genome

Start

End

186029973/186312184 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6083 ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-410-3p ; hsa-mir-1277-5p ; hsa-mir-1295b-3p ; hsa-mir-4789-5p ; hsa-mir-8485 ; hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p

Nearest miRNA

hsa-let-7g/Upstream/544280; hsa-mir-1248/Downstream/474488;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/117745, chr3-CpG: 94/Downstream/48737

Upstream sequence

cttaatcagtatggaggctacccactccacattaccttcttttcaagggcctgtttcccttgcttccataactgttgtgcgtattgacagccaggcttct

Downstream sequence

CATTAAACTGTTAAACTCCGAAAAAACTATAAATCAACATTTTCAAAAGTGAATCTGAAAATCCATATATGAGAGTGGAATTCTAAGGTACATGATAACT