Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015036
Fusion event
HBV-PLG integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp3 X protein
Start
1775
Orient
-
Integrated sequence
TCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTAC| |TAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCC
Host Sequence
Chromosome
chr6
Cytoband
q26
Reference genome
End
161125593/160704561 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/1939808; hsa-mir-1913/Downstream/5804793;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/25137, chr6-CpG: 51/Downstream/62491
Upstream sequence
CTTAtaaggcaggagaatagggaattagggtaaccaagggttaaggcataagcaaaggaacagcaggtgcagccagttctaggcaagattaggcagcata
Downstream sequence
GAGAGTTCAAGTTGGCAGAAAGTGCGGGGTAAAGACATGGATATGGGCCTAAAGCATCTATTTCTTTGTGATCTTTTGATATATCTCTCAAGTGCTTTTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.