VISDB Viral Integration Site DataBase

VIS ID

TVIS10015037

Fusion event

HBV-XBP1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1708

Orient

-

Integrated sequence

CATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATAC| |TTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCAC

Chromosome

chr22

Cytoband

q12.1

Reference genome

Start

End

29192896/28796908 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-127-3p ; hsa-mir-214-3p ; hsa-mir-124-3p ; hsa-mir-625-3p ; hsa-mir-320a ; hsa-mir-93-5p ; hsa-let-7c-5p ; hsa-mir-30a-3p ; hsa-mir-125a-3p ; hsa-mir-320c

Nearest miRNA

hsa-mir-1286/Upstream/336960; hsa-let-7a-3/Downstream/1210141;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/23914, chr22-CpG: 77/Downstream/3186

Upstream sequence

TGGCTACTGCATTTGTTAGTACTTGTTCTTAGGGAGCCATGTAACTTGTTTTCATTATTAGATCTTAGTACTGTTCACTACACACTTAAAAAATGAGTGT

Downstream sequence

CAAGTGCCTTTAGGGGAAGAACACTCTGCCTGCATGAAAATGTCTTAAAACTGAAGGAAAATTTCAAGAACGCTCTTGATCAGAAGTCCAGACTGTAAAC