Basic Information
VIS ID
TVIS10015046
Fusion event
HBV-chr14 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1721
Orient
-
Integrated sequence
GTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTT| |TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA
Host Sequence
Chromosome
chr14
Cytoband
q32.13
Reference genome
GRCh37/hg19
Start
96085136/95618799 (Hg38)
End
96085136/95618799 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1260a/Upstream/480813; hsa-mir-1185-1/Downstream/4490620;
Nearest TSS
ENST00000550708/Upstream/45194; ENST00000555032/Downstream/2115;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/83271, chr14-CpG: 53/Downstream/95120
Upstream sequence
acttaaggtgctggcagggccatggcctctttgaagcctctggggagcatcatttttgcctcttctagctcctggtggctcttgaaagtccttggtgttc
Downstream sequence
cttgacttgtagttgcatcactccaatctctgcctccattgccatgtggctttctcctctctgtgtgtctctctgtatcctctcctcttcctaaaaggac
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate