Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015049
Fusion event
HBV-MYOM1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1883
Orient
+
Integrated sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG| |CCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTA
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
Start
End
3108768/3108770 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-8078/Upstream/2996431; hsa-mir-1-2/Downstream/776583;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/41235, chr18-CpG: 79/Downstream/138525
Upstream sequence
gctgggattacaggtgcggaccaccacacccagctaatttttgtattttcagtagaaacagggtttcaccatgttggccaggctgatctcgaactcctga
Downstream sequence
ccttgtgatccgcctgtcttggcctcccaaagtgctgggataataggcgtgaggcaccgtgtccggccAATGACAGCATTTCAGAATTTCTAACATGCCC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.