Basic Information
VIS ID
TVIS10015053
Fusion event
HBV-chr20 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1892
Orient
+
Integrated sequence
AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG| |GCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTT
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
11962578/11981930 (Hg38)
End
11962578/11981930 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/1332235; hsa-mir-1-1/Downstream/6488685;
Nearest TSS
ENST00000382410/Upstream/60364; ENST00000432244/Downstream/262366;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/90371, chr20-CpG: 217/Downstream/1238093
Nearby gene
BTBD3
Upstream sequence
cccaagtagctgggattatagctatgtgccacgacaccaggctaatttttgtattttaagtagagacagggtttcaccatgttggccaggctgatctcga
Downstream sequence
actccttacctcaagtgatccacctgcctcagcctcccaaaatgctaggatttcaggcgtaagccaccactcctggccCcttagttacttttcagaacaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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