Basic Information
VIS ID
TVIS10015056
Fusion event
HBV-chr21 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1885
Orient
+
Integrated sequence
TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC| |TTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACG
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
9861617/9022784 (Hg38)
End
9861617/9022784 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10396a/Upstream/35119; hsa-let-7c/Downstream/4383600;
Nearest TSS
ENST00000624081/Upstream/4114; ENST00000624052/Downstream/302229;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/34806, chr21-CpG: 20/Downstream/47394
Nearby gene
LOC105372731(+3829) ;
Upstream sequence
CAGATACAAAACTCCCAGAAATTCCATCTTGTCATTTATTTCCACAAGAAAAAACAAGAGACCTGTATTAAAATATCCATTTCTATTAAAATTAATCACA
Downstream sequence
CTAGGTTTCTTCAAATTTTTTTATTAGTAGCTCTTGTTTTCAGCAGTACAATTTCTAatatatatgtgtatatatatttaatatatatatgcacatatac
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate