Basic Information
VIS ID
TVIS10015057
Fusion event
HBV-chrY integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1785
Orient
-
Integrated sequence
CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG| |TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC
Host Sequence
Chromosome
chrY
Reference genome
GRCh37/hg19
Start
13468207/13468207 (Hg38)
End
13468207/13468207 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/8861979; hsa-mir-12120/Downstream/10970;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/562820, chrY-CpG: 33/Downstream/11172
Upstream sequence
acatgcaggttacatagatatacatgtgccatggtggtttgctgcacctatcaacccgtcatctaggttttaagctccacatgcattaggtatttgtcct
Downstream sequence
atcacctgggtgatcagtgcagagatatgtcacaatgcccccataggcagatccaagacaagagtccatcacctgggtgatcagtgcagaaatatgtcac
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate