DCUN1D4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015060
Fusion event
HBV-DCUN1D4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1839
Orient
+
Integrated sequence
AGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTA| |ATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTG
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
52727435/51861269 (Hg38)
End
52727435/51861269 (Hg38)
Orient
+
Location type
Intronic
Target gene
DCUN1D4
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-17-5p ; hsa-mir-27a-3p ; hsa-mir-27b-3p
Nearest miRNA
hsa-mir-12113/Upstream/4208526; hsa-mir-1243/Downstream/851413;
Nearest TSS
ENST00000502981/Upstream/16385; ENST00000504923/Downstream/16187;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/16311, chr4-CpG: 75/Downstream/176616
Upstream sequence
AGACAAATAGTAACCCTCAAGTGGTATTATGAAATTTACTAGCATATATAGGTATACATACACACATATGCATGTTATACAAACCCACATGCACATACAC
Downstream sequence
AGTGTGTGCACACATTTGAATTCTCTTGGGTGTAGGAAGGGCAGTGGGCAGAATGTGGGGTTGGAAGGAAGGGTTTTGTGGAGTGGGGTGGTGAAAGATG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate