Basic Information
VIS ID
TVIS10015061
Fusion event
HBV-LOC101929488 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1006
Orient
-
Integrated sequence
CCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGG| |TCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCA
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
58257849/57345290 (Hg38)
End
58257849/57345290 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101929488
Nearest miRNA
hsa-mir-124-1/Upstream/14449015; hsa-mir-10400/Downstream/4369498;
Nearest TSS
ENST00000518652/Upstream/1483; ENST00000520370/Downstream/147594;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/64965, chr8-CpG: 99/Downstream/649101
Upstream sequence
cccagccTACAGTGAATCTTAAGATGAGTTTTCAAGGGGATGACTATTCAGATAGACATTAGGGAAATCGTATGAGCAAAGGTGTAGAGATGGAAGCAAG
Downstream sequence
cttgagtgtgtgctgatcccttgggatttgatggcaggaacatggcagaagcgttattCCACTGCACTTGATTTCAGTTTGCCCTGTGTAAGCATTCTTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate