Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015062
Fusion event
HBV-PRPSAP2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
2237
Orient
+
Integrated sequence
CAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAG| |AGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAG
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
Start
End
18834580/18931267 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1253/Upstream/590381; hsa-mir-10226/Downstream/413239;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/72727, chr17-CpG: 15/Downstream/40104
Upstream sequence
TGCAACTAAAAAAGGAATAAAAACTTGTGTTTGTGTGTTTTTCTAAAACTTTGTGTTTTGGCAATCGTTTTATAACTAAAATAAAATGAAAGCTAAATCT
Downstream sequence
ACACGCTGTGAATGTTGAAATGTTCATCAGCTTGTTTTCTCTTCTGCAGCTTTGTGGGGGATGCAGTAGCCTCTCAGAGATGTGATATCCTCTGTTCTGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.