Basic Information
VIS ID
TVIS10015063
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp3 X protein
Start
1517
Orient
-
Integrated sequence
GTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCG| |ACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGAC
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
49853483/48940924 (Hg38)
End
49853483/48940924 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/6044649; hsa-mir-10400/Downstream/12773864;
Nearest TSS
ENST00000518652/Upstream/19184; ENST00000522267/Downstream/113387;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/17252, chr8-CpG: 45/Downstream/36903
Nearby gene
SNAI2(No orient, 19483)
Upstream sequence
caatattcatcaaggatattggtctaaaattctctcttttggttttgtctctgcccagctttggtatcaggatgatgctggcctcataaaatgagttagg
Downstream sequence
tttttgtacattgattttgtatcctgagactttgctgaagttgcttatcagcttaaggagacttggggctgagactatggggttttctaaatatacaatc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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