ADH1A _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015065
Fusion event
HBV-ADH1A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3218
Orient
-
Integrated sequence
AGGAAGGCAGCCTACCCCGCTGTCTCCACCTTTGAGAAACACTCATCCTCAGGCCATGCAGTGG| |
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
100226341/99305184 (Hg38)
End
100226341/99305184 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADH1A
miRNAs that regulate target gene
hsa-mir-132-3p
Nearest miRNA
hsa-mir-12113/Upstream/307724; hsa-mir-1243/Downstream/1935611;
Nearest TSS
ENST00000502981/Upstream/14156; ENST00000503257/Downstream/13683;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/216206, chr4-CpG: 40/Downstream/258386
Upstream sequence
GTAATTATACCTATATTTGTTCCCCTTCTCAAATCTTAGCTTTAATTGGAAACTGTTCTCCCAAAAAGACTCCTTACCCAAGAGAAAGTGCACCCTTTTT
Downstream sequence
AAAATGAAAACATTTTTTCCTTATCTATATTTTTAGATTATTTGTTTATACCAGAATTTGAAATTTTTCTCCATGCTCAGAATTTCATTTTAAATATGTT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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