Basic Information
VIS ID
TVIS10015075
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
181
Orient
-
Integrated sequence
ACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCC| |TAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCT
Host Sequence
Chromosome
chr13
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
88395590/87743335 (Hg38)
End
88395590/87743335 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/124595; hsa-mir-1267/Downstream/2487847;
Nearest TSS
ENST00000623511/Upstream/70720; ENST00000430214/Downstream/60029;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/65705, chr13-CpG: 41/Downstream/1619823
Upstream sequence
AGTGAATGTGATATGGTGGTTATGGGGTATCTGTGTTTATATGTGAGTATATTTTCCCCAAAGAGAAGTAGTGTGTCATAGTCACAAACCATCTGCTAAT
Downstream sequence
AAGATTTGTATAAAACTAAAATTTGAAGTTAGAAAAATACTATTATGTGTCTAAATGTGAAATATTAACCATATAACTGTTGCTTCTATATTAGGACCAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate