Basic Information
VIS ID
TVIS10015076
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
2257
Orient
-
Integrated sequence
GTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATT| |TGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACG
Host Sequence
Chromosome
chr13
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
88395609/87743354 (Hg38)
End
88395609/87743354 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/124614; hsa-mir-1267/Downstream/2487828;
Nearest TSS
ENST00000623511/Upstream/70739; ENST00000430214/Downstream/60010;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/65724, chr13-CpG: 41/Downstream/1619804
Upstream sequence
TTATGGGGTATCTGTGTTTATATGTGAGTATATTTTCCCCAAAGAGAAGTAGTGTGTCATAGTCACAAACCATCTGCTAATAAGATTTGTATAAAACTAA
Downstream sequence
AATTTGAAGTTAGAAAAATACTATTATGTGTCTAAATGTGAAATATTAACCATATAACTGTTGCTTCTATATTAGGACCATTTTCAGAGGCATAGTATAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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